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Estrogen Signaling Pathway Steps || Genomic and Nongenomic pathways of steroid hormones

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Along side these issues were countless questions that continue to bewilder many people, one of the most frequently asked question regarding estrogen is how much is too much. Does this compound, which has been proven to have medical benefits cause adverse effect when taken beyond adequate amount? According to the recent findings of Women s Health Initiative in 2004, the daily-recommended intake of estrogen is highly dependent on the preparation used and to the brand name of the chosen estrogen alternative. Many studies have shown that one cause of this unbearable disease is estrogen insufficiency. Every year, there are 500,000 U.S women suffering from osteoporosis cause by this deficiency. Since treatment for osteoporosis cost 10 billion per year, only a few are able to survive this maddening disease across the country. This is usually done in order to avoid possible discomfort and health problem brought by the imbalance estrogen hormone in the system of a woman. The therapy is classified into short-term and long term relief. The short term relief usually lasts for one or two years. On the other hand, there is no exact duration for a long term relief because as long as the patient needs cure in order to lessen the risk, she will be recommended for a thorough treatment. The most common side effects with estrogen hormone are: Softness of the breast, either men or women Inflammation of the ankles and legs Lesser cravings for food Sudden changes in weight Nausea Vomiting Abdominal pains Skin Irritation Other side effects are: Bleeding gums Vaginal bleeding and spotting Changes in menstrual flow Painful menstruation PMS or the pre-menstrual syndrome Vaginal infection such as Candida Diarrhea Loss of scalp hair Migraine Faintness Despair Increased sexual desires Decreased sexual desires Rare side effects include: Blood clotting Sudden feeling to urinate Unclear speech Changes in vision Breathlessness Estrogen hormone should always be balanced. However, it must be noted that even some of the alternatives of hormone replacement products such as the estrogen supplements are not safe at all times. It can sometimes lead to disorders such as heart failures and bone loss. It is true that most of the Estrogen supplements are natural but it does not always follow that these are always safe. During this period, estrogen is found in a normal state. However, if menstruation is noted, that is the time where estrogen is found in a higher level. This is normal because of the release of corpus letuem found inside the eggs cells during this stage. However, there are also moments that the production of estrogen is beyond normal. 

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