This is because, estrogen is found in the eggs produced by the ovaries. Usually, the normal menstrual cycle in a woman s anatomy last for twenty eight to thirty days. During this period, estrogen is found in a normal state. However, if menstruation is noted, that is the time where estrogen is found in a higher level. Aside from the aforementioned physical attributes that distinguish women from men, it is also essential in some body functions. Anatomically, women should have normal estrogen in the body for normal functioning. Health researches show that normal estrogen keeps the normal functioning of women s body. The minimum amount of estrogen can be an effect of the following condition: Fetal demise Anencephaly Maternal ingestion of corticosteroids Placental sulfatase deficiency Progesterone has the following functions: It is the hormone responsible for the preparation of endometrium for nidation. It maintains the normal function of the endometrium It relaxes the myometrium. If there are times that you fail to apply the patch in the affected area make sure that you will still apply it as soon as you remember. But do not dare to apply the patch more than the prescribed because it can cause some side effects. Most often, instead of treating you, it can worsen the condition. Decrease in egg production, low level of sexual desires, lower bone density and muscle firmness as well as skin integrity follows. As the estrogen production starts to diminish in the menopausal period, this marks the transgression of the human cycle. Lastly, this ultimately signals the descent of the human body clock as determined by the particular hormone-estrogen. Thus, if the level of this hormone reduces there is a tendency that a woman will suffer from various disorders. Estrogen cream helps the woman in maintaining a healthy hormone balance especially during the period of menopausal and even beyond. On the other hand, the maintenance of this cream is also quite difficult because if you use it beyond what the doctor prescribed, it can lead to some very serious risks.